Pharmacology Specialist | $200/hr Remote | Mercor
Posted Today by Crossing Hurdles
Negotiable
Undetermined
Remote
United Kingdom
Summary: The role of PK/PD Modeling / Pharmacometrics Lead at Mercor involves evaluating pharmacokinetic/pharmacodynamic models and ensuring their quantitative rigor. The position requires strong expertise in quantitative pharmacology and modeling tools, with a focus on providing credible predictions and identifying potential issues in model outputs. This is a remote, hourly contract position with a commitment of 10–40 hours per week. Compensation ranges from $150 to $200 per hour based on experience and project requirements.
Key Responsibilities:
- Evaluate PK/PD and exposure–response model outputs for plausibility and quantitative rigor.
- Identify non-plausible parameter spaces, unsafe extrapolations, and high-risk assumptions.
- Design clear model evaluation rubrics that separate credible vs. non-credible predictions.
- Define quantitative sanity checks and failure conditions (parameter limits, curve fit quality, coverage issues).
- Provide example “gold-standard” PK/PD fits and concise reasoning behind key modeling decisions.
Key Skills:
- Strong years of experience in quantitative pharmacology, PK/PD modeling, or pharmacometrics.
- Strong hands-on experience with exposure–response, population PK, and parameter estimation.
- Proficiency with NONMEM, Monolix, or similar modeling tools.
- Ability to interpret model results for dose justification and decision-making.
- Skilled at identifying structural issues, poor fits, and unrealistic assumptions in models.
Salary (Rate): £200.00/hr
City: undetermined
Country: United Kingdom
Working Arrangements: remote
IR35 Status: undetermined
Seniority Level: undetermined
Industry: Other
At Crossing Hurdles, we work as a referral partner. We refer candidates to Mercor that collaborates with world’s leading AI research labs to build and train cutting-edge AI models.
Organization: Mercor
Position: PK/PD Modeling / Pharmacometrics Lead
Referral partner: Crossing Hurdles
Type: Hourly Contract
Compensation: $150–$200/hour
Location: Remote
Duration: Varies by project (1–3 months typical)
Commitment: 10–40 hours/week
Role Responsibilities:
- Evaluate PK/PD and exposure–response model outputs for plausibility and quantitative rigor.
- Identify non-plausible parameter spaces, unsafe extrapolations, and high-risk assumptions.
- Design clear model evaluation rubrics that separate credible vs. non-credible predictions.
- Define quantitative sanity checks and failure conditions (parameter limits, curve fit quality, coverage issues).
- Provide example “gold-standard” PK/PD fits and concise reasoning behind key modeling decisions.
Requirements:
- Strong years of experience in quantitative pharmacology, PK/PD modeling, or pharmacometrics.
- Strong hands-on experience with exposure–response, population PK, and parameter estimation.
- Proficiency with NONMEM, Monolix, or similar modeling tools.
- Ability to interpret model results for dose justification and decision-making.
- Skilled at identifying structural issues, poor fits, and unrealistic assumptions in models.
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